Transcription of SYSTEMIC LUPUS ERYTH EMATOSUS: PATHOGENESIS, …
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SYSTEMIC LUPUS ERYTH EMATOSUS: PATHOGENESIS, …
Eular On-line Course on Rheumatic Diseases module n 17 Ricard Cervera, Gerard Espinosa, David D Cruz 1 2007-2009 EULAR SYSTEMIC LUPUS ERYTHEMATOSUS: pathogenesis , CLINICAL MANIFESTATIONS AND DIAGNOSIS INTRODUCTION SYSTEMIC LUPUS erythematosus (SLE) is a multisystem autoimmune disorder with a broad spectrum of clinical presentations (1). There is a peak age of onset among young women between the late teens and early 40 s and a female to male ratio of 9:1. Ethnic groups such as those with African or Asian ancestry are more at risk of developing the disorder and it may be more severe compared to Caucasian patients. SLE is a chronic illness that may be life-threatening when major organs are affected but more commonly results in chronic debilitating ill health.
There are many epidemiological studies on SLE from around the world and there is extensive data from the European Union (EU) and the United States of America (USA) (2-14).
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