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Editorial Commentary on the KDIGO Clinical …

EditorialCommentary on the KDIGO Clinical Practice Guidelinefor GlomerulonephritisNot so long ago, a paper published inKidney Internationalexplored the reasons for the paucity of high-quality clinicaltrials in glomerulonephritis (GN).1 The authors identifiedseveral factors, including the low prevalence of disease, vari-ability in Clinical presentation, variability in treatmentresponses, lack of consensus about definitions, difficulty inrecruiting patients, the high cost of randomized controlledtrials, and the lack of collaborative research efforts. To thislist, I would also add our poor understanding of the patho-genesis of most if not all of the glomerulonephritides com-monly encountered in Clinical practice. This point is relevantbecause it limits the variety of new therapies that we can putup for Clinical trials, and ultimately our ability to punchthrough the therapeutic envelope, so to speak.

Editorial Commentary on the KDIGO Clinical Practice Guideline for Glomerulonephritis Not so long ago, a paper published in Kidney International explored the reasons for the paucity of high-quality clinical

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  Guidelines, Practices, Clinical, Kdigo, Glomerulonephritis, Kdigo clinical, Kdigo clinical practice guideline for glomerulonephritis

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