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EQUINE CUSHING’S DISEASE

1 EQUINE cushing S DISEASE Patrick M. McCue DVM, PhD, Diplomate American College of Theriogenologists EQUINE cushing s DISEASE is a complex progressive DISEASE of the pituitary gland of middle age to older horses. The pituitary gland is a small structure located at the base of the brain which produces hormones that regulate many body functions. cushing s DISEASE occurs when the production of dopamine, a neurotransmitter that normally controls the function of a specific portion of the pituitary gland, decreases. Lack of dopamine results in an increase in the size of the pituitary gland and subsequently an increase in the production of adreno-corticotropic hormone (ACTH) and other proteins from cells of the affected pituitary.

EQUINE CUSHING’S DISEASE Patrick M. McCue DVM, PhD, Diplomate American College of Theriogenologists Equine Cushing’s disease is a complex progressive disease of the pituitary gland of middle age to older horses. The pituitary gland is a small structure located at the base of the brain which produces hormones that regulate many body functions.

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