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EXTERNAL REVIEW – THEOPHYLLINE

REVIEW THEOPHYLLINE Background The current 13th edition of the WHO Model Essential Medicines List (dated April 2003) includes THEOPHYLLINE as an Essential medicine . The listing is as shown below (together with the other respiratory tract medicines listed). Box 1: 13th Model EML listing of medicines acting on the respiratory tract No indication is given as to whether the tablet formulations listed are immediate-release or of a sustained release form. The entry in the WHO Model Formulary is more extensive, as shown in the box on the next page.

theophylline as a specific oral methylxanthine in relation to the listed indications (“chronic asthma including nocturnal asthma; acute severe asthma”), as well as in the management of chronic obstructive pulmonary ... External review Current positioning of the agent in international guidelines 1. Asthma - …

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