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Factsheet on ESBLs

Essex Health Protection Unit Further advice on any of the areas discussed or copies of this sheet may be obtained from the unit: Main office telephone 0845 1550069 Reviewed August 2006 Factsheet on ESBLs What does esbl mean? esbl stands for extended spectrum beta ( ) lactamase. Beta lactamases are enzymes produced by many species of bacteria which destroy one or more antibiotics. It is one of the ways in which bacteria develop resistance. ESBLs are unusual in that as the name suggests they break down an exceptionally wide variety of antibiotics. This can cause problems when treating infected patients, as doctors do not usually use the few remaining effective antibiotics as a first choice.

some newer antibiotics appears to predispose patients to infection with ESBL-producing bacteria which may explain why this has become an issue now.

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