Transcription of Formulation development and evaluation of gabapentin ...
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Submit Manuscript | : API, active pharmaceutical ingredient; MEC, minimum effective concentration; CRDDS, controlled release drug delivery system; MSC, maximum safe concentration; PHN, post herpetic neuralgia; RH, relative humidity; HPMC, hydroxy propyl methyl cellulose; mg, milli gram; gm, grams; ICH, the international conference on harmonization; USP, united states pharmacopeia; NA, not applicable; SR, sustained release; IR, immediate releaseIntroductionImmediate release/Conventional release tablets achieve a rapid onset of action, once they reach the Maximum Effective Concentration; they start to get eliminated from the body. Controlled release tablets of gabapentin are often prescribed for chronic, severe neuronal pain caused as a result of certain long standing diseases. Controlled release tablets are used for a prolonged duration of action with minimal therapeutic effect.
Submit Manuscript | http://medcraveonline.com Abbreviations: API, active pharmaceutical ingredient; MEC, minimum effective concentration; CRDDS, controlled release ...
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