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Framework for Metals Risk Assessment - EPA

EPA 120/R-07/001 | March 2007 Framework for Metals Risk Assessment Office of the Science Advisor Risk Assessment Forum EPA 120/R-07/001 March, 2007 Framework for Metals Risk Assessment Office of the Science Advisor Risk Assessment Forum Environmental Protection Agency Washington, DC 20460 DISCLAIMER This document has been reviewed in accordance with Environmental Protection Agency policy.

Kinetic Modeling.....4-22 4.3.5. Metal Toxicity.....4-23 4.3.5.1. Noncancer Effects of Metals ... PBPK Physiologically based pharmacokinetic PBT Persistent bioaccumulative toxic PBTK Physiologically based toxicokinetic QSAR Quantitative structure -activity relationship

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