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Guide to achieving reliable quantitative LC-MS …

Guide to achieving reliable quantitative LC-MS measurements Guide to achieving reliable quantitative LC-MS measurements RSC Analytical Methods Committee First Edition 2013 Editor Mike Sargent Contributors Ashley Sage Celine Wolff Chris Mussell David Neville Gwyn Lord Mansoor Saeed Rakesh Lad Ruth Godfrey Simon Hird Vicki Barwick Acknowledgements This Guide has been prepared with the assistance of members of the AMC Mass Spectrometry Sub-Committee. Publication of the draft Guide with minor corrections was approved by the AMC at its meeting on 15 November 2013.

Quantitative LC-MS Guide, 1st Ed. 2013 Page 2 There are many different manufacturers of LC and MS systems, each with their own particular traits and operating instructions, but generally they all follow the same principles.

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