Transcription of Helicobacter pylori
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Helicobacter pylori
Page 1 Helicobacter pyloriFact Sheet for Health Care ProvidersUpdated: July 1998 What is H. pylori ? Helicobacter pylori (H. pylori ) is a spiral-shapedbacterium that is found in the gastric mucous layeror adherent to the epithelial lining of the pylori causes more than 90% of duodenal ulcersand up to 80% of gastric ulcers. Before 1982, when this bacterium was discovered,spicy food, acid, stress, and lifestyle wereconsidered the major causes of ulcers. Themajority of patients were given long-termmedications, such as H2 blockers, and morerecently, proton pump inhibitors, without a chancefor permanent cure. These medications relieveulcer-related symptoms, heal gastric mucosalinflammation, and may heal the ulcer, but they doNOT treat the infection. When acid suppression isremoved, the majority of ulcers, particularly thosecaused by H. pylori , recur. Since we now knowthat most ulcers are caused by H. pylori ,appropriate antibiotic regimens can successfullyeradicate the infection in most patients, withcomplete resolution of mucosal inflammation and aminimal chance for recurrence of common is H.
Page 1 Helicobacter pylori Fact Sheet for Health Care Providers Updated: July 1998 What is H. pylori ? Helicobacter pylori (H. pylori ) is a spiral-shaped
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