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Hepatitis E Vaccine: Composition, Safety, …

1 Hepatitis E vaccine : Composition, safety , immunogenicity and efficacy A document prepared for Strategic Advisory Group of Experts on Immunization (SAGE) by the Hepatitis E vaccine Working Group Table of Contents Executive Summary .. 2 Background - Hecolin .. 3 Composition .. 3 safety .. 4 Phase I study .. 5 Phase IIa/b trial .. 5 Phase III trial .. 5 Phase III retrospective cohort study - pregnant women .. 6 Phase III retrospective cohort study: HBsAg-positive individuals .. 7 safety : overall summary .. 7 immunogenicity .. 8 efficacy .. 9 Phase III randomized field trial .. 10 Longer-term efficacy .. 11 efficacy in specific high-risk or other subgroups.

1 Hepatitis E Vaccine: Composition, Safety, Immunogenicity and Efficacy A document prepared for Strategic Advisory Group of Experts on Immunization

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