Transcription of Hydrogen Bonds - Brandeis
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Hydrogen Bonds - Brandeis
Hydrogen BondsHydrogen Bonds have played an incredibly important role in the history of structuralbiology. Both the structure of DNA and of protein a-helices and b-sheets were predictedbased largely on the Hydrogen Bonds these structures form. So understanding hydrogenbonds is clearly important, but much like the hydrophobic effect , Hydrogen Bonds aresurprisingly complex and are not completely understood in every last detail. So take thethings I will tell you with a grain of electrostatic nature of Hydrogen bondsHydrogen Bonds are formed when an electronegative atom approaches a Hydrogen atombound to another electro-negative atom. The most common electro negative atoms inbiochemical systems are oxygen ( ) and nitrogen ( ) while carbon ( ) andhydrogen ( ) are relatively electropositive (the electronegativity values are given onthe Pauling scale, and don t have a direct physical meaning).
bonds is clearly important, but much like the hydrophobic effect, hydrogen bonds are surprisingly complex and are not completely understood in every last detail. So take the things I will tell you with a grain of salt. The electrostatic nature of hydrogen bonds Hydrogen bonds are formed when an electronegative atom approaches a hydrogen atom
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