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  Coordination, Complexes, Coordination complexes

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3 1. Transition Metal Complexes as Drugs Invesitgational New Drugs, December 1995, Volume 13, pages 327-332. Pt complexes have had the most effective medicinal properties against certain types of cancers, but in 1995 the first non platinum transition metal anitcancer agent (Budotitane) reached phase 2 clinical trials. Maximum clinical dose of this compound is 230 mg/m2twice weekly

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and private practice) were asked to (1) participate in opinion surveys and (2) review and comment on drafts of the Guidelines. Third, a random sample of active

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123.702 Organic Chemistry enantiomers cis epoxide mp = 98°C Two chiral centres (diastereoisomers) • A molecule with 1 stereogenic centre exists as 2 stereoisomers or enantiomers • Enantiomers have identical physical properties in an achiral environment 1 HN NH 2 N O OH NH 2 NH N O HO S R Mirror Two enantiomers

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