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Il dolore nel paziente con cancro: un progetto di ricerca

R 20: in cancer patients: a research projectPain afflicts most cancer patients, mainly in the advanced and metastaticphase of the disease. Despite the existence of well-known, publishedguidelines for cancer pain management recommended by the World HealthOrganization (WHO) and the availability of effective treatments for 70-90% of cases, under-treatment is well documented and can involve upto 40% patients. Under-treatment is usually attributed to an incorrect useof opioids. In Italy, opioid consumption rates were among the lowest inEurope until 2000. A recent evaluation of the market sales shows anincrease in opioid use (currently 45 DDD/100000), but there are datasuggesting that it is mostly attributable to one drug, transdermal fact that the sales and prescriptions of other opioids available to cancerpatients in Italy (morphine and buprenorphine) remained constantsuggests that some of the patients treated with fentanyl should have beentreated with oral morphine, suggesting, in turn, that some of theprescriptions were ina

RICERCA SUL CAMPO R&P 2004; 20: 137-145 140 LA SITUAZIONE IN ITALIA Nonostante la disponibilità di un’ampia gamma di farmaci efficaci e di linee guida basate su evidenze scientifiche, è comunque molto ben docu-

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