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IMMUNOLOGY - Elsevier.com

873 IMMUNOLOGYGLOSSARY88 THE IMMUNE RESPONSE SYSTEM92 Innate and adaptive immunity92 Cells and molecules involved in theimmune response93 Antigen-recognition lymphoid cells (B and T lymphocytes) 93 Granulocytes 98 Macrophages 98 Dendritic cells 98 Natural killer cells 99 Cytokines 99 Accessory molecules 103 Other molecules 104 Apoptosis 105 IMMUNOGLOBULINS105 Properties, functions and reactions105 Structure of immunoglobulin molecule108 Clinical considerations109 Paraprotein 109 Macroglobulins 110 Cryoglobulins 110 Cold agglutinins 110 Monoclonal antibodies 110 COMPLEMENT111 The complement system111 Complement pathways111 Complement deficiencies112 HYPERSENSITIVITY112 Classification112 IMMUNODEFICIENCY115 Primary immunodeficiency115B-cell disorders 115T-cell disorders 116 Combined B- and T-cell disorders 116 Neutrophil disorders 117 Secondary immunodeficiency118 Hypogammaglobulinaemia 118T-cell deficiency 118 Hypergammaglobulinaemia 119 AUTOIMMUNE DISEASE120 Explanatory theories for breakdown inself tolerance121 Autoantibodies121 Antinuclear antibodies 122 BLOOD GROUP IMMUNOLOGY123 ABO group123 Rhesus (CDE)

B-cell disorders 115 T-cell disorders 116 Combined B- and T-cell disorders 116 ... Haplotype A set of genetic determinants coded by closely linked ... (Fig 3.1 and Table 3.1) The innate component functions as a first line of defence and involves

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