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INCLUSION COMPLEX SYSTEM; A NOVEL …
Volume 2, Issue 2, May June 2010; Article 006 ISSN 0976 044X. INCLUSION COMPLEX SYSTEM; A NOVEL TECHNIQUE TO IMPROVE THE. SOLUBILITY AND BIOAVAILABILITY OF POORLY SOLUBLE DRUGS: A REVIEW. Patil *, Kadam , Marapur , Kamalapur Department of Pharmaceutics, 's, College of Pharmacy, BLDE university campus, Bijapur-586 103, Karnataka (India). *Email: ABSTRACT. Orally administered drugs completely absorb only when they show fair solubility in gastric medium and such drugs shows good bioavailability. The solubility and dissolution properties of drugs play an important role in the process of formulation development. Problem of solubility is a major challenge for formulation scientist which can be solved by different technological approaches during the pharmaceutical product development work. Solid dispersion, solvent deposition, micronization are some vital approaches routinely employed to enhance the solubility of poorly water soluble drugs. Each approach suffers with some limitations and advantages.
Volume 2, Issue 2, May – June 2010; Article 006 ISSN 0976 – 044X
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