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INDOXACARB - INCHEM

315 INDOXACARBF irst draft prepared byU. Mueller1 and Angelo Moretto21 Office of Chemical Safety, Therapeutic Goods Administration, Canberra, ACT, Australia; and 2 Dipartimento Medicina Ambientale e Sanit Pubblica, Universit di Padova, Padova, Italy 316 Evaluation for acceptable daily 316 Biochemical aspects .. 316 Absorption, distribution and 316 Biotransformation .. 319 Toxicological 319 Acute 319 Oral 319 Dermal administration .. 319 Exposure by inhalation .. 320 Dermal and ocular irritation .. 320 Dermal sensitization .. 320 Short-term studies of 323 Long-term studies of toxicity and 334 Reproductive 336 Multigeneration studies .. 336 Developmental toxicity .. 337 Special 338 Reversibility of haemolytic and body-weight changes. 338 Distribution of 14C-DPX-JW062 in rat erythrocytes .. 339 Haemolytic potential of N-hydroxy-4-(trifluoromethoxy)aniline (INMT713) in rats, dogs, and humans in vitro.

INDOXACARB 31 –3 JMPR 2005 317 Although only sparingly soluble in aqueous media (0.2 g/ml), racemic indoxacarb (DPX-JW062 or DPX-MP062) was suspended in polyethylene glycol (PEG-400) to give a fixed dosage

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