Transcription of Lecture 1 Introduction to Multi-level Models
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Lecture 1 Introduction to Multi-level Models
11 Lecture 1 Introduction to multi -levelModelsCourse web ~fdominic/teaching/bio656 Background on MLMs Main Ideas Accounting for Within-Cluster Associations Marginal & Conditional Models A Simple Example Key MLM components23 The Main Biological, psychological and social processes thatinfluence health occur at many levels : Cell Organ Person Family Neighborhood City Society An analysis of risk factors should consider: Each of these levels Their interactionsMulti-level Models Main IdeaHealthOutcome35 Example: Alcohol Abuse1. Cell: Neurochemistry2. Organ: Ability to metabolize ethanol3. Person: Genetic susceptibility to addiction4. Family: Alcohol abuse in the home5. Neighborhood: Availability of bars6. Society: Regulations; organizations; social normsLevel:6 Example: Alcohol Abuse; Interactions betweenLevels5 Availability of bars and6 State laws about drunk driving4 Alcohol abuse in the family and2 Person s ability to metabolize ethanol3 Genetic predisposition to addiction and4 Household environment6 State regulations about intoxication and3 Job requirementsLevel:47 Notation:PopulationNeighborhood: i=1.
1 1 Lecture 1 Introduction to Multi-level Models Course web site http://www.biostat.jhsph.edu/~fdominic/teaching/bio656/ml.html 2 Statistical Background on …
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