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Maximizing Metabolite Extraction for …

AuthorsTheodore Sana and Steve FischerAgilent Technologies, Inc., Santa Clara, CA, USAM aximizing Metabolite Extraction for comprehensive MetabolomicsStudies of ErythrocytesApplication NoteAbstractMetabolomics is the comparative analysis of metabolites found in sets ofsimilar biological samples. Since metabolites play vital roles in biologicalsystems, metabolomics can be useful for finding and identifying biomarkers, orfor obtaining a better understanding of the effects of drugs or diseases on bothknown and unexpected biological metabolomic research requires effective Metabolite Extraction . Fornon-targeted metabolomics , Extraction methods need to capture a broad rangeof cellular and biofluid metabolites, while excluding components such asproteins that are not intended for analysis. Extraction is made more challengingby the physico-chemical diversity of metabolites and by Metabolite abun-dances that can vary by many orders of , liquid-liquid Extraction is often used to extract metabolites.

Authors Theodore Sana and Steve Fischer Agilent Technologies, Inc., Santa Clara, CA, USA Maximizing Metabolite Extraction for Comprehensive Metabolomics

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  Comprehensive, Maximizing, Extraction, Metabolite, Metabolomics, Maximizing metabolite extraction for, Maximizing metabolite extraction for comprehensive metabolomics

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