Transcription of Method 533: Determination of Per- and Polyfluoroalkyl ...
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Method 533: Determination of Per- and Polyfluoroalkyl ...
Method 533: Determination OF PER- AND. Polyfluoroalkyl SUBSTANCES IN DRINKING WATER BY. ISOTOPE DILUTION ANION EXCHANGE SOLID PHASE. EXTRACTION AND liquid chromatography / tandem . mass spectrometry . Technical questions concerning this analytical Method should be addressed to: Steven C. Wendelken, EPA, Office of Ground Water and Drinking Water, Standards and Risk Management Division, Technical Support Center, 26 W. Martin Luther King Dr. Cincinnati, OH 45268. Phone: (513) 569-7491. Questions concerning this document or policy should be addressed to: Office of Water (MS-140). EPA Document No. 815-B-19-020.
This is a solid phase extraction (SPE) liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of select per- and polyfluoroalkyl substances (PFAS) in drinking water. Method 533 requires the use of MS/MS in Multiple Reaction Monitoring (MRM) mode to enhance selectivity.
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