Transcription of MODULE 10: PHARMACOVIGILANCE
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MODULE 10: PHARMACOVIGILANCE
MODULE 10: PHARMACOVIGILANCE WHO/Petterik Wiggersn1681. INTRODUCTIONThis section introduces the concepts of PHARMACOVIGILANCE and adverse drug reactions, discusses the burden of adverse drug reactions for children and explains the importance of PHARMACOVIGILANCE in the context of antiretroviral therapy (ART). Defining pharmacovigilanceWHO defines PHARMACOVIGILANCE as the science and activities related to the detection, assessment, understanding and prevention of adverse effects or any other possible drug-related problem (1). It focuses on investigating and monitoring adverse drug reactions after medicinal products are licensed (2).
of HIV and to improve maternal health. Global coverage of ART for preventing perinatal transmission and maternal HIV treatment is high, with UNAIDS estimating that coverage of ART among pregnant women living with HIV was 76% in 2016 (22). Consequently, HIV transmission rates are now less than 1% in many high-income
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