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Muscle Edema -Recognizing Patterns and Associated Causes

Muscle Edema - Recognizing Patterns and Associated CausesHierl MS, MD, Yadavalli S, MD, PhD and Marcantonio D, MDBeaumont Health, Royal Oak, MIOakland University William Beaumont School of Medicine, MIDisclosuresThe authors do not have a financial relationship with acommercial organization that may have a direct or indirectinterest in the content. Educational review of Muscle Edema Patterns and distribution Emphasis on findings seen on magnetic resonance imaging (MRI) Correlate Muscle Edema Patterns with relevant clinical history Clinical data often helps in narrowing a differential or in making an accurate diagnosis Discuss relevance of other imaging modalities and usefulness of intravenous contrastGoals and ObjectivesIntroduction Muscle Edema is seen secondary to multiple etiologies including trauma, infectious and inflammatory processes, autoimmune disorders, neoplasms, and denervation injuries On MRI Muscle Edema is characterized by increase in free water within the Muscle Muscle Edema is seen on MRI as increased signal on fluid sensitive sequencesT2 FSHigher signal to noise ratioSpecific fat suppressionSusceptible to inhomogeneous fat suppression STIRL ower signal-to-noise ratioHomogenous fat suppression T1 weighted images useful for evaluating Fatty atrophy of Muscle Subacute hemorrhage in presence of methemoglobin Contrast useful for evaluating for underlying infarction.

Geometric margins – Extends uninterrupted across muscle and subcutaneous fat • Edema signal – Can increase over 12-18 months – Can persist for many years A: Initial Ax T2 FS ... • Important for radiologists to recognize distribution and patterns of muscle edema

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