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National Plague Control Guidelines - NICD

National Plague Control Guidelines TABLE OF CONTENTS. CONTENTS PAGE. PREFACE 3. ACKNOWLEDGEMENTS 4. 1. EPIDEMIOLOGY OF Plague 5. 2. ETIOLOGY OF Plague . Transmission and Plague pathways 5. 3. HUMAN Plague . Clinical manifestations 8. Bubonic Plague 8. Septicaemic Plague 8. Pneumonic Plague 8. Diagnosis of Plague 9. Case definitions of human Plague 9. Laboratory diagnosis of Plague 9. Management of Plague and prevention of spread 9. Specific antibiotic treatment 9. Treatment in pregnancy and children 10. Supportive therapy 10. Post exposure prophylactic therapy 11. Vaccination 11. Prevention and Control of human Plague transmission 11. Notification 11. Samples 11. Isolation 11. Concurrent disinfection 11. Quarantine 12. Protection of contacts 12. Investigation of contacts and source of infection 12. Education 12. Human surveillance 12. Passive surveillance 12. Community surveillance 13.

4 Plague Control Guidelines for South Africa Plague Control Guidelines for South Africa ACKNOWLEDGEMENTS The Plague Control Guidelines were developed by the National Department of Health in collaboration with the Plague Working Group.

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