Transcription of Next-Generation Sequencing Resources for Pathologists
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Next-Generation Sequencing Resources for Pathologists
1 Next-Generation Sequencing Resources for PathologistsIntroduction Next-Generation Sequencing (NGS) has revolutionized biomarker analyses delivering unprecedented multiplexing capabilities. Unlike PCR testing or capillary electrophoresis (CE) based Sequencing (also known as Sanger Sequencing ), NGS can multiplex to assay many genes simultaneously, replacing the need to order multiple tests. Compared to traditional methods, which are often inconclusive and require iterative testing on limited tissue, NGS has the potential to reduce costs and improve patient care, realizing the vision of precision medicine. Increasingly, NGS is being used to understand the genetic changes within cancers, identify the causative variants of rare and inherited disorders, advance prenatal and reproductive care, and anticipate potential adverse reactions to a chosen therapy.
Next-Generation Sequencing Resources for Pathologists Introduction Next-generation sequencing (NGS) has revolutionized biomarker analyses delivering unprecedented multiplexing ... Regulatory Information 1. Collins FS, Hamburg MA. First FDA authorization for next-generation sequencer.
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