Transcription of Nitrofurantoinum - uspbpep.com
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Nitrofurantoinum - uspbpep.com
european pharmacopoeia ml withwater R. Prepare a reference solution in thesame manner using mg ofnitrofural ( ) of the 2 solutions at the absorptionmaximum at 375 the content of C6H6N4O4from the absorbancesmeasured and the concentrations of the from impurities: A, bis[(5-nitrofuran-2-yl)methylene]diazane ,B. (5-nitrofuran-2-yl)methylene :0101corrected [67-20-9]DEFINITIONN itrofurantoin contains not less than per cent andnot more than the equivalent of per cent of 1-[[(5-nitrofuran-2-yl)methylene]amino]i midazolidine-2,4-dione,calculated with reference to the dried yellow, crystalline powder or yellow crystals, odourlessor almost odourless, very slightly soluble in water and inalcohol, soluble in out the test protected from bright prepared for the assay.
EUROPEAN PHARMACOPOEIA 6.0 Nitrogen 100.0 ml with water R.Prepare a reference solution in the same manner using 60.0 mg ofnitrofural CRS.Measurethe absorbances (2.2.25) of the 2 solutions at the absorptionmaximum at 375 nm. Calculate the content of C6H6N4O4 from the absorbances measured and the concentrations of the solutions.
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