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Open Access Research Incidence and prevalence of diabetic ...

1 Farsani sF, et al. BMJ Open 2017;7:e016587. Access AbstrActObjectives To summarise Incidence and prevalence of diabetic ketoacidosis (DKA) in adults with type 1 diabetes (T1D) for the overall patient population and different subgroups (age, sex, geographical region, ethnicity and type of insulin administration).Design systematic literature review (SLR).Data sources Medline (via PubMed) and Embase (1 January 2000 to 23 June 2016).study selection Peer-reviewed observational studies with reported data on the Incidence or prevalence of DKA in T1D adults were included. A single reviewer completed the study screening and selection process and a second reviewer performed an additional screening of approximately 20% of the publications; two reviewers independently conducted the quality assessment; the results were narratively Out of 1082 articles, 19 met the inclusion and exclusion criteria, with two additional studies identified that did not specify the patient age range and are therefore not included in the SLR.

in the USA.6–9 A recent systematic literature review (SLR) reported the incidence of T1D to be 1.5 times higher in males than in females less than 40 years of age.6 Diabetic ketoacidosis (DKA) is a major acute metabolic complication of T1D that is typically marked by acidosis,

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  Review, Literature, Systematic, Systematic literature review

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