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Optical Trapping - MIT

Optical TrappingMIT Department of Physics(Dated: August 11, 2017)An Optical trap or Optical tweezers is a device which can apply and measure piconewton sizedforces on micron sized dielectric objects under a microscope using a highly focused light beam. Itallows very detailed manipulations and measurements of several interesting systems in the fields ofmolecular and cell biology and thus acts as a major tool in biophysics. They are used in biologicalexperiments ranging from cell sorting to the unzipping of DNA.

Aug 11, 2017 · use of optical forces to trap dielectric microspheres held within a thin layer of water and vesicles in onion cells. The typical mechanical forces involved are on the scale of piconewtons (10 12 N). Relative to this scale, hydrody-namical forces (drag and di usion) on the microspheres and vesicles are substantial. Thus, the optical trap pro-

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