Transcription of Pharmacokinetic Training Packet for Pharmacists
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Pharmacokinetic Training Packet for Pharmacists Revised 1/09, 6/12 Original document compiled by: Elizabeth D. Hermsen, , , BCPS-ID Updated by: Alan Gross, , BCPS Thanks to Erin Iselin, Scott McMullen, Chris Shaffer, & Keith Olsen for your thoughtful review! Any questions? Call or email Alan Gross at 2 Table of Contents Pharmacokinetic definitions and principles 3 Aminoglycoside overview 4 Extended-interval (Once daily) aminoglycoside dosing 8 Aminoglycoside Pharmacokinetic calculations 10 Aminoglycoside dosing in patients with cystic fibrosis 12 Vancomycin overview and Pharmacokinetic calculations 15 Clinical Pearls 21 Dialysis Aminoglycosides and Vancomycin 21 TNMC Nephrology Protocol for Vancomycin Dosing 21 Clinical Pharmacokinetic
Jul 03, 2001 · 3 Pharmacokinetic Definitions and Principles Kel, Ke, or Kd or Elimination Rate Constant • The fraction or percentage of the total amount of drug in the body eliminated per unit of time.1 • Estimated with 2 drug levels taken between doses (the slope of the line).
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