Transcription of Potent Compound Handling Operations
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Potent Compound Handling Operations
2011 Particle Sciences, Inc. All rights Compound Handling OperationsBackground Pharmacology is the branch of medicine and biology concerned with the study of the interactions that occur between a living organ-ism and chemicals that affect bio-chemical functions. In the field of pharmacology, potency is a mea-sure of drug activity expressed in terms of the amount required to produce an effect of given inten-sity. A highly Potent drug evokes a larger response at low concen-trations, while a drug of lower po-tency evokes a smaller response at similar concentrations. Occupational health profession-als in the pharmaceutical industry have recognized the potential for occupational disease caused by overexposure to active pharma-ceutical ingredients (APIs).1 Com-pounds that are routinely handled in the biotechnology, pharmaceu-tical and medical device indus-tries (from hereon called pharma-ceutical industry) are unique in that they are designed to have an effect on the human body.
situations during non-routine ac-tivities, such as emergency repair activities. OEBs that are utilized in discovery and early development are initially
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