Transcription of Prenatal Detection of Congenital Heart Defects at the 11 ...
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Prenatal Detection of Congenital Heart Defects at the 11 ...
Prenatal Detection of Congenital HeartDefects at the 11- to 13-Week ScanUsing a Simple Color Doppler ProtocolIncluding the 4-Chamber and 3-Vesseland Trachea Viewsn the past years, plenty of reports about indirect screeningmethods for the diagnosis of Congenital Heart Defects werepublished. They were based on markers of aneuploidy,including nuchal translucency, triuspid regurgitation, and ductusvenosus velocimetric 4 However, the Detection ratesfor Congenital Heart Defects do not exceed 40% for nuchal translu-cency above the 95th percentile alone and 58% for nuchal translucencyabove the same limit combined with a reversed or absent a-wave inthe ductus venosus flow , indirect methods inMarcin Wiechec, MD, Anna Knafel, MD, PhD, Agnieszka Nocun, MDReceived January 31, 2014, from the Chair ofGynecology and Obstetrics, Jagiellonian Univer-sity, Krakow, Poland.
the first trimester are at risk of false-positive findings due to the functional immaturity of the cardiovascular system at this stage of fetal development.
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