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Prothrombin Time (PT) - Quest Diagnostics

CPT:Medicare National Coverage Determination PolicyCMS National Coverage PolicyVisit view current limited coverage tests, reference guides, and policy view the complete policy and the full list of codes, please refer to the CMS website reference85610 Prothrombin Time (PT) Coverage Indications, Limitations, and/or Medical NecessityBasic plasma coagulation function is readily assessed with a few simple laboratory tests: the Partial ThromboplastinTime (PTT), ProthrombinTime (PT), Thrombin Time (TT), or a quantitative fibrinogen determination. The PT test is one in-vitro laboratory test used to assess coagulation . While the PTT assesses the intrinsic limb of the coagulation system, the PT assesses the extrinsic or tissuefactor dependent pathway.

of factor X.Extrinsic pathway factors are produced in the liver and their production is dependent on adequate vitamin K activity. Deficiencies of factors may be related to decreased production or increased consumption of coagulation factors. The PT/INR is most commonly used to measure the effect of warfarin and regulate its dosing.

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