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Review - Respiratory Care

ReviewAirway Pressure Release Ventilation: What Do We Know?Ehab G Daoud MD, Hany L Farag MD, and Robert L Chatburn MHHS RRT-NPS FAARCI ntroductionTerminologyAPRV Versus BIPAPAPRV Versus Conventional VentilationAPRV Versus Other Non-Conventional VentilationAPRV SettingsP High/P LowT High/T LowSettings AdjunctsPressure Support and Automatic Tube CompensationSynchronizationAPRV and WeaningAdvantages of APRVS pontaneous VentilationLong Inflation TimeLung-Protective BenefitsAPRV and MortalityDisadvantages of APRVS pontaneous BreathingWork of BreathingTidal Volume and Minute VentilationPresent and FutureConclusionsAirway pressure release ventilation (APRV) is inverse ratio, pressure controlled, intermittent man-datory ventilation with unrestricted spontaneous breathing. It is based on the principle of open lungapproach. It has many purported advantages over conventional ventilation, including alveolarrecruitment, improved oxygenation, preservation of spontaneous breathing, improved hemodynam-ics, and potential lung-protective effects.

A recent review of 50 published studies of both modes11 showed that 78% of the studies described APRV, while 22% described BIPAP. Extreme inverse I:E ( 2:1) was

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