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RP-HPLC method development and validation for …
*Correspondence: S. Alt n z. Hacettepe University, Faculty of Phar-macy, Department of Analytical Chemistry. 06100 - Ankara- Turkey. E-mail: Journal of Pharmaceutical Sciencesvol. 49, n. 2, , 2013RP- hplc method development and validation for estimation of rivaroxaban in pharmaceutical dosage formsMustafa elebier, Tuba Re ber, Engin Ko ak, Sacide Alt n z*Department of Analytical Chemistry, Faculty of Pharmacy, Hacettepe University, TurkeyRivaroxaban, an anti-clotting medication, acts at a crucial point in the blood-clotting process and stops the formation of blood clots. In this study, RP-HPLC method was developed for the determination of rivaroxaban in tablets (Xarelto (10 mg)). Phenomenex Luna 5 m C18 100 LC Column (250 x mm) was used at 40 oC. Isocratic elution was performed with ACN:Water (55:45 v/v) mixture.
RPHPLC method development and validation for estimation of rivaroxaban in pharmaceutical dosage forms 361 to 1000 µL by adding water. The concentration of RIV
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