Transcription of Section VIII-E: Viral Agents
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Section VIII-E: Viral Agents
200 Biosafety in Microbiological and Biomedical LaboratoriesSection viii -E: Viral AgentsHantavirusesHantaviruses are negative sense RNA viruses belonging to the genus Hantavirus within the family Bunyaviridae. The natural hosts of hantaviruses are rodent species and they occur worldwide. Hantavirus pulmonary syndrome (HPS) is a severe disease caused by hantaviruses such as Sin Nombre virus or Andes virus whose hosts are rodents in the subfamily Sigmodontinae. This subfamily only occurs in the New World, so HPS is not seen outside North and South America. Hantaviruses in Europe and Asia frequently cause kidney disease, called nephropathica epidemica in Europe, and hemorrhagic fever with renal syndrome (HFRS) in InfectionsDocumented laboratory-acquired infections have occurred in individuals working with Extreme caution must be used in performing any laboratory operation that may crea
202 Biosafety in Microbiological and Biomedical Laboratories. of the genus, Pteropus giganteus, is the reservoir for the virus in Bangladesh. 24
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