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SEROTONIN AND BRAIN: EVOLUTION, NEUROPLASTICITY, …

SEROTONIN AND brain : evolution , NEUROPLASTICITY, AND HOMEOSTASISE frain C. AzmitiaDepartment of Biology and Psychiatry, Center for Neural Science, New York UniversityNew York 10003, USAI. IntroductionII. evolution : From Unicellular to HumansIII. Holistic brain Function Starts at DevelopmentIV. Homeostasis of BrainV. Clinical Implications of Loss of HomeostasisReferencesNeurotransmitters are chemicals released by the presynaptic endings ofneurons that have specialized actions through specific receptors on the mem-brane potential of postsynaptic neurons. However, these chemicals have morecomplex functions both within the neuron and on its varied cellular functions include changes in metabolic activities that have consequenceson the plasticity of the neurons.

I. Introduction Thischapter presentsevidence thattheneurotransmitter serotonin(5-hydroxy-tryptamine, 5-HT) functions as a global factor involved in brain homeostasis.

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