Transcription of SIGN142 Osteoporosis
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Management of Osteoporosis and the prevention of fragility fracturesA national clinical guidelineFirst published March 2015 Revised June 2020 Revised January 2021 SIGN142 Key to evidence statements and recommendationsLevels of evidence1++ High-quality meta-analyses, systematic reviews of RCTs, or RCTs with a very low risk of bias1+ Well-conducted meta-analyses, systematic reviews, or RCTs with a low risk of bias1 Meta-analyses, systematic reviews, or RCTs with a high risk of bias2++ High-quality systematic reviews of case-control or cohort studies High-quality case-control or cohort studies with a very low risk of confounding or bias and a high probability that the relationship is causal2+ Well-conducted case-control or
which aimed to prevent fractures in older people by raising the profile of falls, 3 and also in a clinical guideline published by the National Institute for Health and Care Excellence (NICE) in 2013. 4 The guideline also excludes issues surrounding the surgical management of fractures and postoperative care of patients with fractures.
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