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SIGN142 Osteoporosis

Management of Osteoporosis and the prevention of fragility fracturesA national clinical guidelineFirst published March 2015 Revised June 2020 Revised January 2021 SIGN142 Key to evidence statements and recommendationsLevels of evidence1++ High-quality meta-analyses, systematic reviews of RCTs, or RCTs with a very low risk of bias1+ Well-conducted meta-analyses, systematic reviews, or RCTs with a low risk of bias1 Meta-analyses, systematic reviews, or RCTs with a high risk of bias2++ High-quality systematic reviews of case-control or cohort studies High-quality case-control or cohort studies with a very low risk of confounding or bias and a high probability that the relationship is causal2+ Well-conducted case-control or

which aimed to prevent fractures in older people by raising the profile of falls, 3 and also in a clinical guideline published by the National Institute for Health and Care Excellence (NICE) in 2013. 4 The guideline also excludes issues surrounding the surgical management of fractures and postoperative care of patients with fractures.

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  Fall, Fracture

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