Transcription of SIGN142 Osteoporosis
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SIGN142 Osteoporosis
Management of Osteoporosis and the prevention of fragility fracturesA national clinical guidelineFirst published March 2015 Revised June 2020 Revised January 2021 SIGN142 Key to evidence statements and recommendationsLevels of evidence1++ High-quality meta-analyses, systematic reviews of RCTs, or RCTs with a very low risk of bias1+ Well-conducted meta-analyses, systematic reviews, or RCTs with a low risk of bias1 Meta-analyses, systematic reviews, or RCTs with a high risk of bias2++ High-quality systematic reviews of case-control or cohort studies High-quality case-control or cohort studies with a very low risk of confounding or bias and a high probability that the relationship is causal2+ Well-conducted case-control or cohort studies with a low risk of confounding or bias and a moderate probability that the relationship is causal2 Case-control or cohort studies with a high risk of confounding or bias and a significant risk that the relationship is not causal3 Non-analytic studies, eg case reports, case series4 Expert opinionRecommendationsSome recommendations can be made with more certainty than others.
pharmacological, and non-pharmacological treatments to reduce fracture risk, treatment of painful vertebral fractures and systems of care. The assessment and prevention of falls is excluded as ... physiotherapists, occupational therapists and those involved in exercise sciences and nutritional management of people with osteoporosis. Patients ...
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