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Available online at Scholars Research Library Der Pharmacia Lettre, 2012, 4 (5):1574-1586 ( ) ISSN 0975-5071 USA CODEN: DPLEB4 1574 Scholar Research Library Solid dispersion technique for improving solubility of some poorly soluble drugs Mogal S. A2*, Gurjar P. N1, Yamgar D. S2 and Kamod 1 GMSPM S College of Pharmacy, A/P Otur, Pune-412409 s College Of Pharmacy, Vilad Ghat, Ahmednagar ( ). _____ ABSTRACT Solid dispersion is one of these methods, which was most widely and successfully applied to improve the solubility , dissolution rates and consequently the bioavailability of poorly soluble drugs. The Solid dispersion is based on the concept that the drug is dispersed in an inert water-soluble carrier at Solid state. Several water soluble carriers such as methyl cellulose, urea, lactose, citric acid, polyvinyl pyrrolidone and polyethylene glycols 4000 and 6000 are used as carriers for Solid dispersion .
Mogal S. A et al Der Pharmacia Lettre, 2012, 4 (5):1574-1586 _____ 1576
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