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Spectrophotometric method of estimation of …

Journal of Applied Pharmaceutical Science 01 (09); 2011: 177-180 ISSN: 2231-3354 Received on: 11-11-2011 Revised on: 22:11:2011 Accepted on: 05-12-2011 Shyni Bernard Department of Pharmaceutical Chemistry, Malik Deenar College of Pharmacy,Kasaragod, Kerala, India. Molly Mathew Principal, Malik Deenar College of Pharmacy,Kasaragod, Kerala, India. K. L. Senthilkumar Principal,Padmavathi College of Pharmacy, Dharmapuri,Tamil Nadu, India. For Correspondence Shyni Bernard, Nattuvayil House, Vandanpathal ( ), Mundakayam, Kottayam (Dist.),Kerala, India, Pin-686513. Spectrophotometric method of estimation of amlodipine besylate using hydrotropic solubilization Shyni Bernard, Molly Mathew and K. L. Senthilkumar ABSTRACT A novel, simple, fast and reproducible UV Spectrophotometric method was developed using 2M urea solution as hydrotropic solubilizing agent for the estimation of poorly water-soluble drug amlodipine besylate in bulk and in pharmaceutical dosage form.

Journal of Applied Pharmaceutical Science 01 (09); 2011: 177-180 suitably with distilled water to get 10 µg/mL and 15 µg/mL each of amlodipine besylate.

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  Methods, Amlodipine, Spectrophotometric, Spectrophotometric method

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