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Successful Function of Autologous iPSC-Derived Dopamine ...
Brief ReportSuccessful Function of Autologous iPSC-DerivedDopamine neurons following transplantation in aNon-Human Primate Model of Parkinson s DiseaseGraphical AbstractHighlightsdA non-human primate model tests cell transplantation for PDtherapydAutologous iPSC Dopamine neurons can provide long-termfunctional recoverydTransplanted cells survive for up to 2 years and reinnervatethe host brainAuthorsPenelope J. Hallett, Michela Deleidi, ..,Roger D. Spealman, Ole BriefA pre-clinical test of transplantation ofautologous iPSC- derived dopamineneurons in a cynomolgus monkey modelof Parkinson s disease provides proof ofprinciple for long-term innervation andfunctional benefit without a requirementfor et al., 2015, Cell Stem Cell16, 269 274 March 5, 2015 2015 Elsevier Stem CellBrief ReportSuccessful Function of Autologous iPSC-DerivedDopamine neurons following transplantation ina Non-Human Primate Model of Parkinson s DiseasePenelope J.
Brief Report Successful Function of Autologous iPSC-Derived Dopamine Neurons following Transplantation in a Non-Human Primate Model of Parkinson’s Disease
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