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1 Plasmodium Life Cycle The malaria parasite exhibits a complex life cycle involving an insect vector (mosquito) and a vertebrate host (human). Four Plasmodium species infect humans: P. falciparum, P. vivax, P. ovale and P. malariae.All four species exhibit a similar life cycle with only minor variations.

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4 Garcia (Giemsa Stain) The morphology of these changes in the life cycle and within the RBCs can cause confusion when examining blood films prepared from this blood.

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4. Malaria is a leading cause of infectious disease. Over 300 million people in the tropics are infected each year, and the death rate is 2 million people per year.

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