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Symptom Management Guidelines: CANCER – …
Symptom Management guidelines : CANCER RELATED DIARRHEA Definition CANCER Related Diarrhea (CRD): An abnormal increase in stool frequency, volume, and liquidity that is different from the usual patterns of bowel elimination; results from CANCER or related treatment(s) Contributing Factors CANCER Related Neuroendocrine tumors ( VIPomas, carcinoid, gastrinomas) Lymphoma Graft vs. host disease after bone marrow transplant CANCER Treatment Related Capecitabine 5 fluorouracil Irinotecan Leucovorin Most small molecule oral tyrosine kinase inhibitors Immunotherapy Checkpoint inhibitors ( Ipilimumab) Biotherapy ( high dose Interferon or Interleukin 2) Radiation Therapy Pelvis, abdomen, lumbar, para-aortic fields Surgical History Celiac plexus block Large or small bowel resection Cholecystectomy Pancreaticoduodenectomy (whipple procedure) Vagotomy Terminal ileal resection and loss of ileocecal valve Medications Laxatives ( stool softeners, stimulant bulk laxatives) Antibiotics ( cephaliexin, amoxicillin, clindamyci)
Symptom Management Guidelines: CANCER – RELATED DIARRHEA . Definition Cancer – Related Diarrhea (CRD): An abnormal increase in stool frequency, volume, and liquidity that is different from the
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