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Symptom Management Guidelines: CONSTIPATION

Symptom Management Guidelines: CONSTIPATION Definition(s) CONSTIPATION : A subjective experience of an unsatisfactory defecation characterized by infrequent stools and/or difficult stool passage ( straining, incomplete evacuation, hard/lumpy stools, prolonged time to pass stool, need for manual maneuvers) Contributing Factors Chemotherapy Agents Vinca alkaloids ( vincristine, vinblastine, vinorelbine) Platinums ( carboplatin, oxaliplatin) Taxanes ( paclitaxel) Thalidomide Medications Opioids Vitamin Supplements ( calcium and iron) Antiemetics ( 5-HT3 antagonists- ondansetron, granisetron) Drugs with anticholinergic effects ( antidepressants, antihistamines, antiparkinsonisms)

Appendix A: Pharmacological Agents that may be used to Manage Constipation below The information contained in these documents is a statement of consensus of BC Cancer professionals regarding their views of currently accepted approaches to treatment.

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