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The Right Analytical Method for the Right Application: TOC ...

GEWater & Process TechnologiesAnalytical Instrumentsimagination at workPaperThe Right Analytical Method for the Right Application: TOC analysis for Cleaning ValidationAdvances in technologies and mounting manufacturingcosts are leading the global pharmaceutical industry toevaluate alternate means to enable greater efficiency andproductivity. In this highly competitive industry, it is vital toensure the highest possible drug quality while eliminatinghigh production costs and unnecessarily lengthy validationwork. Interest in Total Organic Carbon (TOC) analysis as anon-specific Method for cleaning validation has grownconsiderably in recent years because specific analyticaltesting like High Performance Liquid Chromatography(HPLC) has proven to be a bottleneck in the cleaning valida-tion process, significantly contributing to equipmentdowntime after paper investigates the advantages of using a non-spe-cific Method for cleaning validation over more traditionalanalytical methods.

GE Water & Process Technologies Analytical Instruments imagination at work Paper The Right Analytical Method for the Right Application: TOC Analysis for Cleaning Validation

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