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This work is licensed under a Creative Commons Attribution -NonCommercial-ShareAlikeLice nse. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this 2006, The Johns Hopkins University and Benjamin Caballero. All rights reserved. Use of these materials permitted only in accordance with license rights granted. Materials provided AS IS ; no representations or warranties provided. User assumes all responsibility for use, and all liability related thereto, and must independently review all materials for accuracy and efficacy. May contain materials owned by others. User is responsible for obtaining permissions for use from third parties as NutrientsBenjamin Caballero, MD, PhDJohns Hopkins UniversitySection AAntioxidant Nutrients4 Antioxidant Nutrients Ascorbic acid Alpha-tocopherol Beta-carotene Selenium Manganese5 Oxidants and AntioxidantsAntioxidants Free radical scavengers: Extracellular/circulating CellularXCytosolicXMembrane-boundPro-Oxi dants Substrate oxidation Antimicrobial defense Radiation Sunlight Ionized compounds Aging Oxygen6 What Is a Free Radical?

5 Oxidants and Antioxidants Antioxidants Free radical scavengers: −Extracellular/ circulating −Cellular XCytosolic XMembrane-bound Pro-Oxidants Substrate oxidation Antimicrobial defense Radiation Sunlight Ionized compounds Aging Oxygen

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