Transcription of Understanding asthma pathophysiology, diagnosis, and ...
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Understanding asthma pathophysiology, diagnosis, and management Learn about new research findings and current treatment strategies for this common disorder. By Shari J. Lynn, MSN, RN, and Kathryn Kushto-Reese, MS, RN. A CHRONIC inflammatory airway from various host factors, environ- even though obvious signs and disorder, asthma is marked by air- mental factors, or a combination. symptoms of asthma may not al- way hyperresponsiveness with re- Host factors include gender, obesi- ways occur. current episodes of wheezing, ty, and genetics. Genetic factors in- Bronchospasms, edema, exces- coughing, tightness of the chest, clude atopy. Defined as a genetic sive mucus, and epithelial and and shortness of breath. Typically, tendency to develop allergic dis- muscle damage can lead to bron- these episodes are associated with eases, such as asthma and allergic choconstriction with broncho- airflow obstruction that may be re- rhinitis, atopy commonly is linked spasm.
Understanding asthma pathophysi-ology helps you understand how the condition is diagnosed and treated. Our knowledge of asthma pathogenesis has changed dramati-cally in the last 25 years, as re - searchers have found various asth - ma phenotypes. Asthma involves many patho - physiologic factors, including bronchiolar inflammation with
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