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Understanding asthma pathophysiology, diagnosis, and ...

Understanding asthma pathophysiology, diagnosis, and management Learn about new research findings and current treatment strategies for this common disorder. By Shari J. Lynn, MSN, RN, and Kathryn Kushto-Reese, MS, RN. A CHRONIC inflammatory airway from various host factors, environ- even though obvious signs and disorder, asthma is marked by air- mental factors, or a combination. symptoms of asthma may not al- way hyperresponsiveness with re- Host factors include gender, obesi- ways occur. current episodes of wheezing, ty, and genetics. Genetic factors in- Bronchospasms, edema, exces- coughing, tightness of the chest, clude atopy. Defined as a genetic sive mucus, and epithelial and and shortness of breath. Typically, tendency to develop allergic dis- muscle damage can lead to bron- these episodes are associated with eases, such as asthma and allergic choconstriction with broncho- airflow obstruction that may be re- rhinitis, atopy commonly is linked spasm.

Understanding asthma pathophysi-ology helps you understand how the condition is diagnosed and treated. Our knowledge of asthma pathogenesis has changed dramati-cally in the last 25 years, as re - searchers have found various asth - ma phenotypes. Asthma involves many patho - physiologic factors, including bronchiolar inflammation with

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