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Unit 8. Introduction to Survival Analysis - UMass

BIOSTATS 640 Spring 2020 8. Introduction to Survival Analysis - R Users Page 1 of 53 Nature Population/ Sample Observation/ Data Relationships/ Modeling Analysis / Synthesis Unit 8. Introduction to Survival Analysis Another difficulty about statistics is the technical difficulty of calculation. Before you can even make a mistake in drawing your conclusion from the correlations established by your statistics, you must ascertain the correlations. - George Bernard Shaw Censored data is tricky. Suppose you are interested in studying Survival following heart transplant surgery. A comparison group might be similarly sick patients who do not undergo transplant surgery. All other things being equal, do surgically treated patients have longer Survival times than non-surgically treated patients? How to proceed? One approach might be to do a logistic regression Analysis with outcome defined as 0/1 occurrence of death by 1 year.

Survival Analysis Methodology addresses some unique issues, among them: 1. “At risk”. This needs to be defined for each survival analysis setting. An “at risk” group is a collection of “like” individuals who are similar with respect to everything (they have similar “profiles” on the explanatory variables) except the one (or

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