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Unsupervised Anomaly Detection with Generative Adversarial ...

To be published in the proceedings of IPMI 2017 Unsupervised Anomaly Detection withGenerative Adversarial Networks to GuideMarker DiscoveryThomas Schlegl1,2?, Philipp Seeb ock1,2, Sebastian M. Waldstein2,Ursula Schmidt-Erfurth2, and Georg Langs11 Computational Imaging Research Lab, Department of Biomedical Imaging andImage-guided Therapy, Medical University Vienna, Doppler Laboratory for Ophthalmic Image Analysis, Department ofOphthalmology and Optometry, Medical University Vienna, models that capture imaging markers relevant fordisease progression and treatment monitoring is challenging. Models aretypically based on large amounts of data with annotated examples ofknown markers aiming at automating Detection . High annotation ef-fort and the limitation to a vocabulary of known markers limit thepower of such approaches.

GANs enable to learn generative models generating detailed realistic im-ages [9,10,11]. Radford et al. [12] introduced deep convolutional generative ad-versarial networks (DCGANs) and showed that GANs are capable of capturing semantic image content enabling vector arithmetic for visual concepts. Yeh et

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