Transcription of Urinary Tract Infections - WHO
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Urinary Tract Infections - WHO
Urinary Tract Infections Leading cause of morbidity and health care expenditures in persons of all ages. An estimated 50 % of women report having had a UTI at some point in their lives. million office visits and more than 1 million hospitalizations, for an overall annual cost > $1 Ulleryd, Sahlgrenska University Hospital, G teborg, Sweden VirulenceHost factorsInfectionNo infectionUTIs may occur either because ofthe pathogenicity of the organism,the susceptibility of the host or acombination of both factorsVirulence factors of the gram-negative uropathogens E. coli and P. mirabilisHost defenses Host defenses Antibacterial properties of urineAntibacterial properties of urine Osmolality (extremes of high or low osmolalities inhibit bacterial growth) High urea concentration High organic acid concentration pHAntiAnti--adherence mechanismsadherence mechanisms Bacterial interference (naturally endogenous bacteria in the urethra, vagina, and periurethral region) Urinary oligosaccharides (have the potential to)
Urinary Tract Infections Leading cause of morbidity and health care expenditures in persons of all ages. An estimated 50 % of women report having had a …
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