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Vitamin A deficiency - WHO

SummaryVitamin A deficiency is a common form of micronutrient malnutritionaffecting of preschool-age children and of pregnant published literature linking Vitamin A interventions to cause-specific child mortality due to measles, diarrhoea, malaria and other infec-tious diseases and to all-cause maternal mortality was comprehensivelyreviewed. Randomized controlled trial data of Vitamin A interventionsand survival were used to estimate the risk of mortality associated withvitamin A deficiency . The published relative risks were adjusted for theestimated prevalence of deficiency at study baseline. Summary relativerisks were calculated from meta-analyses (for measles, diarrhoea, andother infectious disease causes of child mortality) or from single studies(malaria mortality among children and all-cause maternal mortality).The estimated relative risks associated with Vitamin A deficiency inchildren were (95% CI ) for measles mortality, (95% CI ) for diarrhoea mortality, (95% CI )for malaria mortality, (95% CI ) for other infectiousdisease mortality and (95% CI ) for all-cause available evidence suggests that nearly 800 000 deaths worldwidecan be attributed to Vitamin A deficiency among women and 20 24% of child mortality from measles, diarrhoea andmalaria and 20% of all-cause m

function, eye health, vision, growth and survival in human beings (National Research Council 1989). Although animal studies that identi-fied vitamin A as a necessary factor for rat growth were conducted in the early 1900s and the chemical structure of the vitamin was elucidated over 20 years later, reports describing the link between xerophthalmia

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