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ActA M dicA Grupo nGeles. volumen 9, No. 2, abril- junio 201183 ART CULO DE REVISI n portalJos Luis Ibarrola-Calleja,* Francisco N ez B, Mauricio Rodr guez G, Jaime Ord ez-C spedes SummaryPortal hypertension (HP) is a complex handling pathologi-cal condition. It is among the ten more frequent causes of mortality in Mexico and is defined as the increase of the portal system (SP) pressure over 12 mmHg. The most frequent etiology is hepatic cirrhosis (CH), so the HP sinusoidal intrahepatic type has the higher incidence. The pathophysiology of the HP is produced by an incre-ment of splachnic vascular resistance and blood volume, conditions that result in systemic alterations and vascular and microvascular modifications, secondary to hormonal, endothelial and neuronal products, leading to all the clinical manifestations.

Ibarrola-Calleja JL y cols. 84 ActA MédicA Grupo ÁnGeles.Volumen 9, No. 2, abril-junio 2011 www.medigraphic.org.mx plénico, terminando en el lecho sinusoidal hepático. Conformada por la unión de las venas mesentérica

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